4-(Chloromethyl)-1,3-thiazole → 2-hydroxy-N-[2-[4-[3-methyl-4-(1,3-thiazol-4-ylmethoxy)anilino]quinazolin-5-yl]oxypropyl]acetamide
Reaction equation
[Cl:1][CH2:2][c:3]1[n:4][cH:5][s:6][cH:7]1.[OH:8][CH2:9][C:10](=[O:11])[NH:12][CH2:13][CH:14]([CH3:15])[O:16][c:17]1[c:18]2[c:19]([NH:27][c:28]3[cH:29][c:30]([CH3:35])[c:31]([OH:34])[cH:32][cH:33]3)[n:20][cH:21][n:22][c:23]2[cH:24][cH:25][cH:26]1>>[CH2:2]([c:3]1[n:4][cH:5][s:6][cH:7]1)[O:34][c:31]1[c:30]([CH3:35])[cH:29][c:28]([NH:27][c:19]2[c:18]3[c:17]([O:16][CH:14]([CH2:13][NH:12][C:10]([CH2:9][OH:8])=[O:11])[CH3:15])[cH:26][cH:25][cH:24][c:23]3[n:22][cH:21][n:20]2)[cH:33][cH:32]1Participants
3
Sources & evidence
- ORD record
- ord-818cdfc55f444e359033cf8cabde55b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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