N-(benzo[1,3]dioxol-5-ylmethyl)-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide → Methyl 4-{3-[(benzo[1,3]dioxol-5-ylmethyl)carbamoyl]-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylcarbamoyl}cyclohexanecarboxylate

HRID 1115218Notes

Reaction equation

HRID 1115218 reaction equation
[CH3:24][O:25][C:26](=[O:27])[CH:28]1[CH2:29][CH2:30][CH:31]([C:34](=[O:35])[Cl:36])[CH2:32][CH2:33]1.[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([CH2:10][NH:11][C:12](=[O:13])[c:14]1[c:15]3[c:16]([s:17][c:18]1[NH2:19])[CH2:20][CH2:21][CH2:22][CH2:23]3)[cH:9]2>>[O:1]1[CH2:2][O:3][c:4]2[c:5]1[cH:6][cH:7][c:8]([CH2:10][NH:11][C:12](=[O:13])[c:14]1[c:15]3[c:16]([s:17][c:18]1[NH:19][C:34]([CH:31]1[CH2:30][CH2:29][CH:28]([C:26]([O:25][CH3:24])=[O:27])[CH2:33][CH2:32]1)=[O:35])[CH2:20][CH2:21][CH2:22][CH2:23]3)[cH:9]2

Participants

3

Reactant 2

HCID 11782481N-(benzo[1,3]dioxol-5-ylmethyl)-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamideHCID 15380636Methyl 4-(chlorocarbonyl)cyclohexane-1-carboxylate

Product 1

HCID 15380637Methyl 4-{3-[(benzo[1,3]dioxol-5-ylmethyl)carbamoyl]-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylcarbamoyl}cyclohexanecarboxylate

Sources & evidence

ORD record
ord-cee48d0cb8994069bc11e0a0a31573e1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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