7-Bromo-4-(2-chlorophenyl)-9-methoxy-3a,4,5,10c-tetrahydro-1H-[1]benzofuro[3,2-e]isoindole-1,3(2H)-dione → 7-Bromo-4-(2-chlorophenyl)-9-methoxy-1H-[1]benzofuro[3,2-e]isoindole-1,3(2H)-dione

Participants

Role	Name	HCID	Charge
Reactant	7-Bromo-4-(2-chlorophenyl)-9-methoxy-3a,4,5,10c-tetrahydro-1H-[1]benzofuro[3,2-e]isoindole-1,3(2H)-dione	HCID 21980489	—
Catalyst	Manganese dioxide	HCID 14801	—
Product	7-Bromo-4-(2-chlorophenyl)-9-methoxy-1H-[1]benzofuro[3,2-e]isoindole-1,3(2H)-dione	HCID 21980347	67%

Reaction Steps

Aromatisation of (860) prepared as described in example442 with MnO2 using the procedure described in example 79 gave the dibenzofuran (861) as a yellow solid (67%). 1H NMR δ [(CD3)2SO] 8.22 (d, J=2.6 Hz, 1H), 8.14 (s, 1H), 7.62 (m, 2H), 7.48 (m, 3H), 3.98 (s, 3H). MH−:458,457,456,454.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07094798B1
Source dataset	uspto-grants-2006_08
ORD ID	ord-6037c376f6cf4a77b61b13054950d1d6
Source note	uspto-grants-2006_08