Bicarbonate Ion → Methyl1-tert-butoxycarbonyl-4-fluoropyrrolidine-2-carboxylate

HRID 1115326Notes

Reaction equation

HRID 1115326 reaction equation
[C:20](=[O:21])([OH:22])[O-:23].[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:7][CH:8]([OH:10])[CH2:9]1.[Cl:25][CH2:26][Cl:27].[F-:18].[Na+:19].[Na+:24]>>[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:7][CH:8]([F:18])[CH2:9]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 28179Fluoride IonHCID 51482991-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 11608471Methyl1-tert-butoxycarbonyl-4-fluoropyrrolidine-2-carboxylate

Sources & evidence

ORD record
ord-d3ceb5c8782e4558bcfcbda4f8934e79
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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