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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1115358Generated: October 25, 2026

Potassium Cation → Tert-butyl 4-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3-(hydroxymethyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/1115358

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantSodium ionHCID 923—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
ReactantIodide IonHCID 30165—
Reactant4-N-Boc-2-hydroxymethylpiperazineHCID 22386508—
Reactant2-[4-(Bromomethyl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-olHCID 23527396—
ProductTert-butyl 4-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3-(hydroxymethyl)piperazine-1-carboxylateHCID 87253414—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-35a25667cf5e47d3b9ee282e1637aff0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)