3,3,3-Trifluoropropylamine → N-(4-fluorobenzyl)-4-methyl-2-(2-oxo-3-(3,3,3-trifluoropropylamino)pyrrolidin-1-yl)thiazole-5-carboxamide
Reaction equation
[Br:8][CH:9]1[C:10](=[O:31])[N:11]([c:14]2[s:15][c:16]([C:20](=[O:21])[NH:22][CH2:23][c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[c:17]([CH3:19])[n:18]2)[CH2:12][CH2:13]1.[F:1][C:2]([CH2:3][CH2:4][NH2:5])([F:6])[F:7]>>[F:1][C:2]([CH2:3][CH2:4][NH:5][CH:9]1[C:10](=[O:31])[N:11]([c:14]2[s:15][c:16]([C:20](=[O:21])[NH:22][CH2:23][c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[c:17]([CH3:19])[n:18]2)[CH2:12][CH2:13]1)([F:6])[F:7]Participants
3
Sources & evidence
- ORD record
- ord-7b849c563972489f8f28191a9643a8db
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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