Methanol → 4-[3-(3-Fluoro-6-methoxyquinolin-4-yl)propyl]-1-[2-(3,4,5-trifluorophenoxy)ethyl]piperidine-4-carboxylic acid
Reaction equation
[CH3:48][OH:49].[F:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([O:38][CH3:39])[cH:9][c:10]2[c:11]1[CH2:12][CH2:13][CH2:14][C:15]1([C:33](=[O:34])[O:35][CH2:36][CH3:37])[CH2:16][CH2:17][N:18]([CH2:21][CH2:22][O:23][c:24]2[cH:25][c:26]([F:32])[c:27]([F:31])[c:28]([F:30])[cH:29]2)[CH2:19][CH2:20]1.[Na+:41].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[OH-:40]>>[F:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([O:38][CH3:39])[cH:9][c:10]2[c:11]1[CH2:12][CH2:13][CH2:14][C:15]1([C:33](=[O:34])[OH:35])[CH2:16][CH2:17][N:18]([CH2:21][CH2:22][O:23][c:24]2[cH:25][c:26]([F:32])[c:27]([F:31])[c:28]([F:30])[cH:29]2)[CH2:19][CH2:20]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ee1279348e4943f7a54d6317e0a0ad26
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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