HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 111572Generated: October 26, 2026
Dimethylformamide → 5-[3-(tert-Butyl-dimethyl-silanyloxy)-benzylcarbamoyl]-3-trifluoromethyl-thiophene-2-carboxylic acid methyl ester
https://huagongshe.com/reaction/111572
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Hexafluorophosphate | HCID 9886 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | O-benzotriazol-1-yl-tetramethyluronium | HCID 130500 | — |
| Reactant | 3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]benzenemethanamine | HCID 22266169 | — |
| Reactant | 5-(Methoxycarbonyl)-4-(trifluoromethyl)thiophene-2-carboxylic acid | HCID 68226602 | — |
| Product | 5-[3-(tert-Butyl-dimethyl-silanyloxy)-benzylcarbamoyl]-3-trifluoromethyl-thiophene-2-carboxylic acid methyl ester | HCID 68227101 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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| ORD ID | ord-1c60981d01564069bba8432b9a36359a |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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