4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine → 1-Benzyl-3-[2-[4-[1-(4-fluoro-benzyl)-1H-benzoimidazol-2-yl]-4-hydroxy-piperidin-1-yl]-ethyl]-3-(phenylmethyl)-2-oxo-pyrrolidine
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9](=[O:26])[C:10]([CH2:13][CH2:14][S:15]([CH3:16])(=[O:17])=[O:18])([CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:11][CH2:12]1.[F:27][c:28]1[cH:29][cH:30][c:31]([CH2:32][n:33]2[c:34]([C:42]3([OH:48])[CH2:43][CH2:44][NH:45][CH2:46][CH2:47]3)[n:35][c:36]3[c:37]2[cH:38][cH:39][cH:40][cH:41]3)[cH:49][cH:50]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9](=[O:26])[C:10]([CH2:13][CH2:14][N:45]2[CH2:44][CH2:43][C:42]([c:34]3[n:33]([CH2:32][c:31]4[cH:30][cH:29][c:28]([F:27])[cH:50][cH:49]4)[c:37]4[c:36]([n:35]3)[cH:41][cH:40][cH:39][cH:38]4)([OH:48])[CH2:47][CH2:46]2)([CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:11][CH2:12]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a2e3d1b2061b44e1b21d8d5c5777c8b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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