1-Bromo-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester → 1-Cyano-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:25])[c:8]2[c:9]([O:16][c:17]3[c:18]([O:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]3)[cH:10][cH:11][cH:12][c:13]2[c:14]1[OH:15].[Cu:26][C:27]#[N:28]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([C:27]#[N:28])[c:8]2[c:9]([O:16][c:17]3[c:18]([O:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]3)[cH:10][cH:11][cH:12][c:13]2[c:14]1[OH:15]Participants
3
Sources & evidence
- ORD record
- ord-fa599aa04a504571b88d6418292d8e0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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