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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1116305Generated: November 3, 2026

Chloride → 7-chloro-1-[(1-cyclopropyl-2,2,2-trifluoroethyl)amino]-5H-pyrido[4,3-b]indole-4-carbonitrile

https://huagongshe.com/reaction/1116305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantSodium ionHCID 923—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantPalladiumHCID 23938—
ReactantDibenzylidene acetoneHCID 95417—
ReactantBinap, (A+-)-HCID 634876—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant1,7-dichloro-5H-pyrido[4,3-b]indole-4-carbonitrileHCID 56595057—
ReactantHCID 178514192HCID 178514192—
Product7-chloro-1-[(1-cyclopropyl-2,2,2-trifluoroethyl)amino]-5H-pyrido[4,3-b]indole-4-carbonitrileHCID 76371298—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-772b032a946b476e92ba70a77fdef953
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)