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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1116727Generated: October 27, 2026

1-(2-Hydroxyethyl)piperazine → 1-(5-Tert-butylisoxazol-3-yl)-3-(3-(6-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-7-methoxyquinazolin-4-ylthio)phenyl)urea

https://huagongshe.com/reaction/1116727

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant1-(5-Tert-butylisoxazol-3-yl)-3-(3-(6-(2-chloroethoxy)-7-methoxyquinazolin-4-ylthio)phenyl)ureaHCID 66876702—
Product1-(5-Tert-butylisoxazol-3-yl)-3-(3-(6-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)-7-methoxyquinazolin-4-ylthio)phenyl)ureaHCID 58267883—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-e7f252d8dcc94cb3bce750cfa5d17807
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)