1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → 6-{3-[3-Fluoro-4-(2-piperidin-1-ylethoxy)phenylamino]pyridin-4-yl}naphthalen-2-ol
Reaction equation
[Br:20][c:21]1[cH:22][cH:23][c:24]([O:25][CH2:26][CH2:27][N:28]2[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2)[c:34]([F:35])[cH:36]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:7][cH:8]1)[cH:9][c:10](-[c:11]1[cH:12][cH:13][n:14][cH:15][c:16]1[NH2:17])[cH:18][cH:19]2.[F:37][c:38]1[cH:39][c:40]([NH:53][c:54]2[cH:55][n:56][cH:57][cH:58][c:59]2-[c:60]2[cH:61][c:62]3[cH:63][cH:64][c:65]([O:70][CH3:71])[cH:66][c:67]3[cH:68][cH:69]2)[cH:41][cH:42][c:43]1[O:44][CH2:45][CH2:46][N:47]1[CH2:48][CH2:49][CH2:50][CH2:51][CH2:52]1>>[F:37][c:38]1[cH:39][c:40]([NH:53][c:54]2[cH:55][n:56][cH:57][cH:58][c:59]2-[c:60]2[cH:61][c:62]3[cH:63][cH:64][c:65]([OH:70])[cH:66][c:67]3[cH:68][cH:69]2)[cH:41][cH:42][c:43]1[O:44][CH2:45][CH2:46][N:47]1[CH2:48][CH2:49][CH2:50][CH2:51][CH2:52]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-298d71d7d0d3493f997e9f8cf8b3c5d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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