tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate → 3-({[4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

HRID 1117342Notes

Reaction equation

HRID 1117342 reaction equation
[C:27]([CH3:28])([CH3:29])([CH3:30])[O:31][C:32](=[O:33])[N:34]1[CH2:35][CH:36]([CH2:39][NH2:40])[CH2:37][CH2:38]1.[CH:1]1([CH2:4][O:5][c:6]2[c:7](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[c:21]([C:24](=[O:25])[OH:26])[cH:22][nH:23]4)[c:8]3[c:9]([cH:13][cH:14]2)[O:10][CH2:11][O:12]3)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[c:21]([C:24](=[O:26])[NH:40][CH2:39][CH:36]3[CH2:35][N:34]([C:32]([O:31][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:33])[CH2:38][CH2:37]3)[cH:22][nH:23]4)[c:8]3[c:9]([cH:13][cH:14]2)[O:10][CH2:11][O:12]3)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 2756485tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylateHCID 668660154-(5-Cyclopropylmethoxy-1,3-benzodioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid

Product 1

HCID 668675163-({[4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-0611d2554cdd4c3dabf5ef94e046c41b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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