Tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate → 4-(Piperidin-4-yloxy)pyridin-2(1H)-one

HRID 1117362Notes

Reaction equation

HRID 1117362 reaction equation
[CH3:22][S:23]([c:24]1[cH:25][cH:26][c:27](-[n:28]2[cH:29][cH:30][c:31]([O:32][CH:33]3[CH2:34][CH2:35][N:36]([C:37]([O:38][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:43])[CH2:44][CH2:45]3)[cH:46][c:47]2=[O:48])[cH:49][cH:50]1)(=[O:51])=[O:52].[O:1]=[c:2]1[nH:3][cH:4][cH:5][c:6]([O:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:13][CH2:14]2)[cH:7]1>>[O:1]=[c:2]1[nH:3][cH:4][cH:5][c:6]([O:8][CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:7]1

Participants

3

Reactant 2

HCID 25204174Tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylateHCID 67366878Tert-butyl 4-(2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate

Product 1

HCID 673661594-(Piperidin-4-yloxy)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-d569b2340b7d4c95a99be8d5b8b9d3f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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