Palladium → 3-(1-benzenesulfonyl-3-cyano-1H-indole-5-carbonyl)-3-benzyl-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:4]([CH3:5])([CH3:6])([CH3:7])[O:8][C:9](=[O:10])[N:11]1[CH2:12][C:13]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([C:23](=[O:24])[c:25]2[cH:26][c:27]3[c:28]([I:43])[cH:29][n:30]([S:34](=[O:35])(=[O:36])[c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[c:31]3[cH:32][cH:33]2)[CH2:14][CH2:15]1.[CH2:100]1[O:101][CH2:102][CH2:103][O:104][CH2:105]1.[CH:46](=[CH:47][C:48]([CH:49]=[CH:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)=[O:57])[c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1.[CH:64](=[CH:65][C:66]([CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1)=[O:75])[c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1.[CH:82](=[CH:83][C:84]([CH:85]=[CH:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1)=[O:93])[c:94]1[cH:95][cH:96][cH:97][cH:98][cH:99]1.[Cu:1][C:2]#[N:3].[Pd:44].[Pd:45]>>[C:2](#[N:3])[c:28]1[c:27]2[cH:26][c:25]([C:23]([C:13]3([CH2:16][c:17]4[cH:18][cH:19][cH:20][cH:21][cH:22]4)[CH2:12][N:11]([C:9]([O:8][C:4]([CH3:5])([CH3:6])[CH3:7])=[O:10])[CH2:15][CH2:14]3)=[O:24])[cH:33][cH:32][c:31]2[n:30]([S:34](=[O:35])(=[O:36])[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:29]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8c5d14d21f554e81bc342645dcb37c92
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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