4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 2-(4-Chloro-phenyl)-2-[4-(1H-pyrazol-4-yl)-phenyl]-morpholine
Reaction equation
[CH3:21][C:22]1([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27][B:28]([c:29]2[cH:30][n:31][nH:32][cH:33]2)[O:34]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([c:14]3[cH:15][cH:16][c:17]([I:20])[cH:18][cH:19]3)[O:9][CH2:10][CH2:11][NH:12][CH2:13]2)[cH:6][cH:7]1.[cH:35]1[cH:36][cH:37][c:38]([P:39]([Pd:40]([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[P:79]([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)[c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[cH:110][cH:111]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([c:14]3[cH:15][cH:16][c:17](-[c:29]4[cH:30][n:31][nH:32][cH:33]4)[cH:18][cH:19]3)[O:9][CH2:10][CH2:11][NH:12][CH2:13]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-a834087900f143a79cb2e0745485ea27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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