4-Hydroxypyrrolidine → HCID 178421890, compound

HRID 1117696Notes

Reaction equation

[NH2:1][c:2]1[n:3][c:4]([N:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12](-[c:19]4[cH:20][c:21]([C:25](=[O:26])[OH:27])[n:22][cH:23][cH:24]4)[cH:13][cH:14][c:15]3[CH2:16][CH:17]2[CH3:18])[n:7]1.[OH:35][CH:36]1[CH2:37][NH:38][CH2:39][CH2:40]1>>[NH2:1][c:2]1[n:3][c:4]([N:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12](-[c:19]4[cH:20][c:21]([C:25](=[O:27])[N:38]5[CH2:37][CH:36]([OH:35])[CH2:40][CH2:39]5)[n:22][cH:23][cH:24]4)[cH:13][cH:14][c:15]3[CH2:16][CH:17]2[CH3:18])[n:7]1

Participants

Reactant 2

HCID 982104-Hydroxypyrrolidine

HCID 594023354-{2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}pyridine-2-carboxylic acid

Product 1

HCID 178421890HCID 178421890, compound

Sources & evidence

ORD record: ord-924b80b9fb95450d9b10ff7ae1175dba
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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