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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1117757Generated: October 26, 2026

1,1-Dichloroethane → 4-{2-[5-(2-Cyano-4-fluorophenoxy)-indazol-1-yl]-ethyl}-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1117757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1-DichloroethaneHCID 6365—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant5-Fluoro-2-[1-(2-oxoethyl)-1H-indazol-5-yloxy]-benzonitrileHCID 57418772—
Product4-{2-[5-(2-Cyano-4-fluorophenoxy)-indazol-1-yl]-ethyl}-piperazine-1-carboxylic acid tert-butyl esterHCID 67410568—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-52263333df46439288f417c1dc70c86c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)