Methanol → 2,2,2-Trifluoro-1-{6-hydroxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)phenyl]-3,4-dihydro-1H-isoquinolin-2-yl}ethanone
Reaction equation
[B:1]([Br:2])([Br:3])[Br:4].[CH3:37][OH:38].[Cl:39][CH2:40][Cl:41].[F:5][C:6]([C:7](=[O:8])[N:9]1[CH:10]([c:21]2[cH:22][cH:23][c:24]([O:27][CH2:28][CH2:29][N:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[cH:25][cH:26]2)[c:11]2[cH:12][cH:13][c:14]([O:19][CH3:20])[cH:15][c:16]2[CH2:17][CH2:18]1)([F:35])[F:36]>>[F:5][C:6]([C:7](=[O:8])[N:9]1[CH:10]([c:21]2[cH:22][cH:23][c:24]([O:27][CH2:28][CH2:29][N:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[cH:25][cH:26]2)[c:11]2[cH:12][cH:13][c:14]([OH:19])[cH:15][c:16]2[CH2:17][CH2:18]1)([F:35])[F:36]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-7642fa60a3d540f69165a99c81b12daf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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