Dimethyl Sulfoxide → 5-Chloro-N-((1-(2-(2-hydroxyethylamino)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

HRID 1118470Notes

Reaction equation

HRID 1118470 reaction equation
[CH3:34][S:35]([CH3:36])=[O:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[c:17]([F:29])[cH:18][c:19](-[n:22]4[c:23](=[O:28])[cH:24][cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1.[NH2:30][CH2:31][CH2:32][OH:33]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[c:17]([NH:30][CH2:31][CH2:32][OH:33])[cH:18][c:19](-[n:22]4[c:23](=[O:28])[cH:24][cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 700EthanolamineHCID 24760453HCID 24760453, compound

Product 1

HCID 247605295-Chloro-N-((1-(2-(2-hydroxyethylamino)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

Sources & evidence

ORD record
ord-38a415df95df4d8a94a01a8fa936e398
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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