3-bromo-N-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide → 3'-[6-Methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-biphenyl-3-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

HRID 1118500Notes

Reaction equation

HRID 1118500 reaction equation
[Br:27][c:28]1[cH:29][c:30]([S:34](=[O:35])(=[O:36])[NH:37][C:38]([CH2:39][OH:40])([CH3:41])[CH3:42])[cH:31][cH:32][cH:33]1.[CH3:1][c:2]1[cH:3][c:4](-[c:17]2[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[cH:5][c:6](-[c:8]2[cH:9][c:10]([B:14]([OH:15])[OH:16])[cH:11][cH:12][cH:13]2)[n:7]1>>[CH3:1][c:2]1[cH:3][c:4](-[c:17]2[cH:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[cH:5][c:6](-[c:8]2[cH:9][c:10](-[c:28]3[cH:29][c:30]([S:34](=[O:35])(=[O:36])[NH:37][C:38]([CH2:39][OH:40])([CH3:41])[CH3:42])[cH:31][cH:32][cH:33]3)[cH:11][cH:12][cH:13]2)[n:7]1

Participants

3

Reactant 2

HCID 435019003-bromo-N-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamideHCID 602093413-[6-Methyl-4-(4-trifluoromethyl-phenyl)pyridin-2-yl]-benzeneboronic acid

Product 1

HCID 602094613'-[6-Methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-biphenyl-3-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

Sources & evidence

ORD record
ord-06e239be30394fe4bd6f083fac73ad7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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