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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1118751Generated: October 29, 2026

1,2-Dimethoxyethane → Ethyl 2-(5-chloro-4'-methyl-6-(2,2,2-trifluoroethoxy) biphenyl-3-yl)-3-cyclopropylpropanoate

https://huagongshe.com/reaction/1118751

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
ReactantFluoride IonHCID 28179—
ReactantTolylboronic acidHCID 79799—
ReactantCesium cationHCID 104967—
ReactantEthyl 2-(3-bromo-5-chloro-4-(2,2,2-trifluoroethoxy)phenyl)-3-cyclopropylpropanoateHCID 57995641—
ProductEthyl 2-(5-chloro-4'-methyl-6-(2,2,2-trifluoroethoxy) biphenyl-3-yl)-3-cyclopropylpropanoateHCID 57995605—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-79fb89655f9347cb905dbaf19e818858
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)