N,N-Dimethyl-1H-benzimidazol-2-amine → 1-(4-((2-(2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-1-yl)ethanone

HRID 1118769Notes

Reaction equation

HRID 1118769 reaction equation
[CH3:28][N:29]([c:30]1[n:31][c:32]2[c:33]([nH:34]1)[cH:35][cH:36][cH:37][cH:38]2)[CH3:39].[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][CH:13]1[CH2:14][CH2:15][N:16]([C:19]([CH3:20])=[O:21])[CH2:17][CH2:18]1)[n:11]2>>[c:2]1(-[n:31]2[c:30]([N:29]([CH3:28])[CH3:39])[n:34][c:33]3[c:32]2[cH:38][cH:37][cH:36][cH:35]3)[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][CH:13]1[CH2:14][CH2:15][N:16]([C:19]([CH3:20])=[O:21])[CH2:17][CH2:18]1)[n:11]2

Participants

3

Reactant 2

HCID 17846N,N-Dimethyl-1H-benzimidazol-2-amineHCID 584049991-(4-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-1-yl)ethanone

Product 1

HCID 533792421-(4-((2-(2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-1-yl)ethanone

Sources & evidence

ORD record
ord-dbb8f4757ab24368acdd676dc70f58a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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