Ethanol → tert-Butyl 4-(pyridin-3-yl)piperidine-1-carboxylate

HRID 1119018Notes

Reaction equation

HRID 1119018 reaction equation
[CH3:20][CH2:21][OH:22].[OH-:23].[OH-:25].[Pd+2:24].[n:1]1[cH:2][c:3]([C:7]2=[CH:12][CH2:11][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:9][CH2:8]2)[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]2)[cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 589134081,1-Dimethylethyl 3′,6′-dihydro[3,4′-bipyridine]-1′(2′H)-carboxylate

Product 1

HCID 22061323tert-Butyl 4-(pyridin-3-yl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-34d2f79878d54b6c9f3338a0ebd04186
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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