N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide → 5-{4-[4-Difluoromethyl-6-(6-trifluoromethyl-pyridin-3-yl)-pyrimidin-2-yl]-pyridin-2-yl}-thiophene-2-sulfonic-acid tert-butylamide
Reaction equation
[C:27]([CH3:28])([CH3:29])([CH3:30])[NH:31][S:32](=[O:33])(=[O:34])[c:35]1[s:36][c:37]([B:40]2[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]2)[cH:38][cH:39]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][c:10](-[c:17]3[cH:18][n:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[cH:11][c:12]([CH:14]([F:15])[F:16])[n:13]2)[cH:7]1>>[c:2]1(-[c:37]2[s:36][c:35]([S:32]([NH:31][C:27]([CH3:28])([CH3:29])[CH3:30])(=[O:33])=[O:34])[cH:39][cH:38]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][c:10](-[c:17]3[cH:18][n:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[cH:11][c:12]([CH:14]([F:15])[F:16])[n:13]2)[cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-9be1935bbc8e419282771f01623123c3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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