Ethanol → 4-[4-(5-Bromo-3-methyl-2-pyridinyl)-2-methylpiperazin-1-yl]-6-(4-fluorophenyl)-2-(2-methylpyrrolidin-1-yl)pyrimidine
Reaction equation
[Br:21][c:22]1[cH:23][c:24]([CH3:35])[c:25]([N:28]2[CH2:29][CH:30]([CH3:34])[NH:31][CH2:32][CH2:33]2)[n:26][cH:27]1.[CH3:41][CH2:42][OH:43].[Cl:1][c:2]1[n:3][c:4]([N:15]2[CH:16]([CH3:20])[CH2:17][CH2:18][CH2:19]2)[n:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[cH:7]1.[Na+:40].[O-:36][C:37]([OH:38])=[O:39]>>[c:2]1([N:31]2[CH:30]([CH3:34])[CH2:29][N:28]([c:25]3[c:24]([CH3:35])[cH:23][c:22]([Br:21])[cH:27][n:26]3)[CH2:33][CH2:32]2)[n:3][c:4]([N:15]2[CH:16]([CH3:20])[CH2:17][CH2:18][CH2:19]2)[n:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-18d1cc361c214febaec2e158a21a3743
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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