1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one → Methyl 6-[2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-1-ylmethyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-5-carboxylate

HRID 1119499Notes

Reaction equation

HRID 1119499 reaction equation
[Br:1][CH2:2][c:3]1[c:4]([C:19](=[O:20])[O:21][CH3:22])[c:5]2[c:6]([n:7]([CH2:14][CH:15]([CH3:16])[CH3:17])[c:8](=[O:13])[n:9]([CH3:12])[c:10]2=[O:11])[s:18]1.[CH3:23][n:24]1[c:25](=[O:33])[nH:26][c:27]2[c:28]1[cH:29][cH:30][cH:31][cH:32]2>>[CH2:2]([c:3]1[c:4]([C:19](=[O:20])[O:21][CH3:22])[c:5]2[c:6]([n:7]([CH2:14][CH:15]([CH3:16])[CH3:17])[c:8](=[O:13])[n:9]([CH3:12])[c:10]2=[O:11])[s:18]1)[n:26]1[c:25](=[O:33])[n:24]([CH3:23])[c:28]2[c:27]1[cH:32][cH:31][cH:30][cH:29]2

Participants

3

Reactant 2

HCID 5905401-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-oneHCID 16102871Methyl 6-bromomethyl-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate

Product 1

HCID 69197857Methyl 6-[2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-1-ylmethyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-5-carboxylate

Sources & evidence

ORD record
ord-429fede5d2d5487fa08c86ee9ffcff79
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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