2-Fluoro-3-methoxyphenylboronic acid → 1-(2'-Fluoro-3'-methoxybiphenyl-3-yl)-1-(2-methoxypyrimidin-5-yl)-1H-isoindol-3-amine

HRID 1119587Notes

Reaction equation

HRID 1119587 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]2([c:18]3[cH:19][n:20][c:21]([O:24][CH3:25])[n:22][cH:23]3)[N:9]=[C:10]([NH2:17])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1.[F:26][c:27]1[c:28]([B:35]([OH:36])[OH:37])[cH:29][cH:30][cH:31][c:32]1[O:33][CH3:34]>>[c:2]1(-[c:28]2[c:27]([F:26])[c:32]([O:33][CH3:34])[cH:31][cH:30][cH:29]2)[cH:3][c:4]([C:8]2([c:18]3[cH:19][n:20][c:21]([O:24][CH3:25])[n:22][cH:23]3)[N:9]=[C:10]([NH2:17])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 49857442-Fluoro-3-methoxyphenylboronic acidHCID 59596264HCID 59596264, compound

Product 1

HCID 248747411-(2'-Fluoro-3'-methoxybiphenyl-3-yl)-1-(2-methoxypyrimidin-5-yl)-1H-isoindol-3-amine

Sources & evidence

ORD record
ord-bbe62b4df0ec40ee8e56de0906e41489
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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