1-[5-(o-chlorophenyl)-2,3-dihydro-1,3,3-trimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]-3-(2-hydroxyethyl)urea → 7-amino-5-(o-chlorophenyl)-1,3-dihydro-1,3,3-trimethyl-2H-1,4-benzodiazepin-2-one

HRID 1119712Notes

Reaction equation

HRID 1119712 reaction equation
[Cl:1][c:2]1[c:3]([C:8]2=[N:9][C:10]([CH3:24])([CH3:25])[C:11](=[O:23])[N:12]([CH3:22])[c:13]3[c:14]2[cH:15][c:16]([N:19]=[C:20]=[O:21])[cH:17][cH:18]3)[cH:4][cH:5][cH:6][cH:7]1.[Cl:26][c:27]1[cH:28][cH:29][cH:30][cH:31][c:32]1[C:33]1=[N:54][C:51]([CH3:52])([CH3:53])[C:49](=[O:50])[N:47]([CH3:48])[c:46]2[c:34]1[cH:35][c:36]([NH:37][C:38]([NH:39][CH2:40][CH2:41][OH:42])=[O:43])[cH:44][cH:45]2>>[Cl:1][c:2]1[c:3]([C:8]2=[N:9][C:10]([CH3:24])([CH3:25])[C:11](=[O:23])[N:12]([CH3:22])[c:13]3[c:14]2[cH:15][c:16]([NH2:19])[cH:17][cH:18]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 205061411-[5-(o-chlorophenyl)-2,3-dihydro-1,3,3-trimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]-3-(2-hydroxyethyl)ureaHCID 20506146[5-(o-chlorophenyl)-2,3-dihydro-1,3,3-trimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]isocyanate

Product 1

HCID 205061787-amino-5-(o-chlorophenyl)-1,3-dihydro-1,3,3-trimethyl-2H-1,4-benzodiazepin-2-one

Sources & evidence

ORD record
ord-e8fa49f2e5fd436591610224af32b7a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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