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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1119902Generated: October 30, 2026

Water → 5-((Tert-butyldimethylsilyl)oxy)-1-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-2-methylenepentan-1-one

https://huagongshe.com/reaction/1119902

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantHydrogen iodideHCID 24841—
ReactantMagnesiumHCID 5462224—
Reactant4-Bromo-4-pentenyl tert-butyl(dimethyl)silyl etherHCID 15600092—
Reactant2,4-Difluoro-5-(pyrimidin-5-yl)benzaldehydeHCID 86685345—
Product5-((Tert-butyldimethylsilyl)oxy)-1-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-2-methylenepentan-1-oneHCID 86685346—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-ad4f5d6c9581405299b97577afa3df79
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)