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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 111996Generated: October 26, 2026

Ethanol → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[4-(methylsulfonyl)phenyl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/111996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantPotassium CationHCID 813—
ReactantCarbonate IonHCID 19660—
Reactant1-Bromo-4-(methylsulphonyl)benzeneHCID 77014—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[4-(methylsulfonyl)phenyl]amino}thiophene-3-carboxamideHCID 44610063—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-19206ff3a0304f168bf03ab78e5ad8aa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)