Potassium Cation → N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-N-(carboethoxymethyl)-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine

HRID 1120061Notes

Reaction equation

HRID 1120061 reaction equation
[Br:29][CH2:30][C:31](=[O:32])[O:33][CH2:34][CH3:35].[C:1](=[O:2])([O:3][CH3:4])[CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([CH2:13][CH:14]([CH3:15])[NH:16][CH2:17][CH:18]([c:19]2[n:20][c:21]([C:24]([F:25])([F:26])[F:27])[s:22][cH:23]2)[OH:28])[cH:11][cH:12]1.[C:36](=[O:37])([O-:38])[O-:39].[CH3:42][CH2:43][C:44](=[O:45])[CH3:46].[K+:40].[K+:41]>>[C:1](=[O:2])([O:3][CH3:4])[CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([CH2:13][CH:14]([CH3:15])[N:16]([CH2:17][CH:18]([c:19]2[n:20][c:21]([C:24]([F:25])([F:26])[F:27])[s:22][cH:23]2)[OH:28])[CH2:30][C:31](=[O:32])[O:33][CH2:34][CH3:35])[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6569Methyl Ethyl KetoneHCID 7748Ethyl bromoacetateHCID 19660Carbonate IonHCID 14347763N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine

Product 1

HCID 19974198N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-N-(carboethoxymethyl)-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine

Sources & evidence

ORD record
ord-6deab6d773d44ed5b3c9af5d1da561f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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