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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1120129Generated: October 30, 2026

Tetrahydrofuran → 2-(2-{2-[(2-Tert-butoxy-1,1-dimethyl-2-oxoethyl)thio]-1,3-thiazol-4-yl}ethoxy)-5-iodobenzoic acid methyl ester

https://huagongshe.com/reaction/1120129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantMethyl 5-IodosalicylateHCID 248910—
ReactantDiethyldiazodicarboxylateHCID 14357405—
Reactant2-{[4-(2-Hydroxyethyl)-1,3-thiazol-2-yl]thio}-2-methylpropionic acid tert-butyl esterHCID 59759352—
Product2-(2-{2-[(2-Tert-butoxy-1,1-dimethyl-2-oxoethyl)thio]-1,3-thiazol-4-yl}ethoxy)-5-iodobenzoic acid methyl esterHCID 59759313—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-69bfcea95cbf477f93d451d8b9380084
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)