Ethyl chloroformate → 4-[5-(3-Iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid ethyl ester
Reaction equation
[CH2:24]([CH3:25])[O:26][C:27](=[O:28])[Cl:29].[CH3:30][C:31]([CH3:32])([CH3:33])[CH2:34][C:35]([N:36]1[CH2:37][CH2:38][N:39]([c:40]2[cH:41][cH:42][c:43]([C:44]([NH:45][c:46]3[cH:47][cH:48][c:49]([CH3:50])[c:51]([I:52])[cH:53]3)=[O:54])[cH:55][n:56]2)[CH2:57][CH2:58]1)=[O:59].[I:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([N:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[cH:15][cH:16]2)=[O:23])[cH:5][cH:6][c:7]1[CH3:8]>>[I:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([N:17]3[CH2:18][CH2:19][N:20]([C:27]([O:26][CH2:24][CH3:25])=[O:28])[CH2:21][CH2:22]3)[cH:15][cH:16]2)=[O:23])[cH:5][cH:6][c:7]1[CH3:8]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7c9d57699842470f964ff764dd21a7c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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