Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate → 4-[N-(4-bromophenyl)-N-[[3-(3,4,5-trimethoxyphenyl)pyridin-5-yl]methyl]amino]-1-(tert-butoxycarbonyl)piperidine

HRID 1120398Notes

Reaction equation

HRID 1120398 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:6][cH:7]1.[Cl:22][CH2:23][c:24]1[cH:25][c:26](-[c:30]2[cH:31][c:32]([O:40][CH3:41])[c:33]([O:38][CH3:39])[c:34]([O:36][CH3:37])[cH:35]2)[cH:27][n:28][cH:29]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]([CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[CH2:23][c:24]2[cH:25][c:26](-[c:30]3[cH:31][c:32]([O:40][CH3:41])[c:33]([O:38][CH3:39])[c:34]([O:36][CH3:37])[cH:35]3)[cH:27][n:28][cH:29]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 11210451Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylateHCID 225578743-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine

Product 1

HCID 225578534-[N-(4-bromophenyl)-N-[[3-(3,4,5-trimethoxyphenyl)pyridin-5-yl]methyl]amino]-1-(tert-butoxycarbonyl)piperidine

Sources & evidence

ORD record
ord-444cd687304644538441c82d16ca8e87
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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