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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1120410Generated: October 27, 2026

1,4-Dioxane → 2-(2-Chloro-5-fluoro-phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopentylmethyl-amide

https://huagongshe.com/reaction/1120410

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
Reactant2-Chloro-5-fluoroanilineHCID 2736509—
Reactant2-Chloro trifluoromethyl-pyrimidin-5-carboxylic acid (cyclopentylmethyl)-amideHCID 57982607—
Product2-(2-Chloro-5-fluoro-phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopentylmethyl-amideHCID 57982660—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-eee5fd8c3519403b8cfdc9405df82835
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)