Acetic Acid → 7-Methoxy-4,5-dihydro-1H-benzo[D]azepin-2(3H)-one

HRID 112061Notes

Reaction equation

HRID 112061 reaction equation
[C:29]([OH:30])(=[O:31])[CH3:32].[CH2:1]([O:2][C:3](=[O:4])[N:11]1[C:12](=[O:24])[CH2:13][c:14]2[c:15]([cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]2)[CH2:16][CH2:17]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH3:27][OH:28].[H:25][H:26]>>[NH:11]1[C:12](=[O:24])[CH2:13][c:14]2[c:15]([cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]2)[CH2:16][CH2:17]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 887MethanolHCID 235442487-Methoxy-2-oxo-1,2,4,5-tetrahydrobenzo[d]azepine-3-carboxylic acid benzyl esterHCID 178418361HCID 178418361, compound

Product 1

HCID 135206897-Methoxy-4,5-dihydro-1H-benzo[D]azepin-2(3H)-one

Sources & evidence

ORD record
ord-6922bee149de4afdb929d59cf38fe602
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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