2-Fluoro-6-(trifluoromethyl)benzoyl chloride → 2-fluoro-N-[4-methyl-3-(tetrahydro-2H-pyran-4-ylcarbonyl)-4,6-dihydrothieno[2,3-c]furan-2-yl]-6-(trifluoromethyl)benzamide
Reaction equation
[F:19][c:20]1[c:21]([C:22](=[O:23])[Cl:24])[c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]1.[NH2:1][c:2]1[c:3]([C:11](=[O:12])[CH:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:4]2[c:5]([s:10]1)[CH2:6][O:7][CH:8]2[CH3:9]>>[NH:1]([c:2]1[c:3]([C:11](=[O:12])[CH:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:4]2[c:5]([s:10]1)[CH2:6][O:7][CH:8]2[CH3:9])[C:22]([c:21]1[c:20]([F:19])[cH:28][cH:27][cH:26][c:25]1[C:29]([F:30])([F:31])[F:32])=[O:23]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-17f79680a79948b0b5f05346340cd4cb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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