Methanol → 7-Amino-2-(2-fluoro-ethyl)-3,3-dimethyl-2,3-dihydro-isoindol-1-one
Reaction equation
[CH2:1]([N:8]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:24]1)[c:9]1[cH:10][cH:11][cH:12][c:13]2[c:17]1[C:16](=[O:18])[N:15]([CH2:19][CH2:20][F:21])[C:14]2([CH3:22])[CH3:23])[c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH3:31][OH:32]>>[NH2:8][c:9]1[cH:10][cH:11][cH:12][c:13]2[c:17]1[C:16](=[O:18])[N:15]([CH2:19][CH2:20][F:21])[C:14]2([CH3:22])[CH3:23]Participants
3
Sources & evidence
- ORD record
- ord-714a6355ab1d42f8b988c82cfa29c39b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…