Dichloromethane → 2-ethyl-4-(tetrahydro-2H-pyran-4-yloxy)-N'-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)cyclopentanecarbohydrazide

HRID 1121911Notes

Reaction equation

HRID 1121911 reaction equation
[CH2:22]([CH3:23])[CH:24]1[CH:25]([C:36](=[O:37])[OH:38])[CH2:26][CH:27]([O:29][CH:30]2[CH2:31][CH2:32][O:33][CH2:34][CH2:35]2)[CH2:28]1.[Cl:63][CH2:64][Cl:65].[NH:1]([NH2:2])[c:3]1[n:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([S:12](=[O:13])(=[O:14])[c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)[cH:10][cH:11]2.[P-:39]([F:40])([F:41])([F:42])([F:43])([F:44])[F:45].[n:46]1([O:47][C:48]([N:49]([CH3:50])[CH3:51])=[N+:52]([CH3:53])[CH3:54])[c:55]2[n:56][cH:57][cH:58][cH:59][c:60]2[n:61][n:62]1>>[NH:1]([NH:2][C:36]([CH:25]1[CH:24]([CH2:22][CH3:23])[CH2:28][CH:27]([O:29][CH:30]2[CH2:31][CH2:32][O:33][CH2:34][CH2:35]2)[CH2:26]1)=[O:37])[c:3]1[n:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([S:12](=[O:13])(=[O:14])[c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)[cH:10][cH:11]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 580098102-Hydrazinyl-5-tosyl-5H-pyrrolo[2,3-b]pyrazineHCID 585577642-ethyl-4-(tetrahydro-2H-pyran-4-yloxy)cyclopentanecarboxylic acid

Product 1

HCID 585579512-ethyl-4-(tetrahydro-2H-pyran-4-yloxy)-N'-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)cyclopentanecarbohydrazide

Sources & evidence

ORD record
ord-f72735aac3c94742bdda68fe9cd580ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…