Isopropyl 5-[acetyl-(3,5-bistrifluoromethylbenzyl)amino]-8-amino-2,3,4,5-tetrahydrobenzo[b]azepine-1-carboxylate → Isopropyl 5-[Acetyl-(3,5-bis-trifluoromethyl-benzyl)-amino]-9-amino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylate
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]([CH:5]1[c:6]2[c:7]([c:18]([Br:22])[cH:19][cH:20][cH:21]2)[N:8]([C:12](=[O:13])[O:14][CH:15]([CH3:16])[CH3:17])[CH2:9][CH2:10][CH2:11]1)[CH2:23][c:24]1[cH:25][c:26]([C:34]([F:35])([F:36])[F:37])[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1.[C:38]([N:41]([CH2:39][c:40]1[cH:42][c:43]([C:44]([F:45])([F:46])[F:47])[cH:48][c:49]([C:50]([F:51])([F:52])[F:53])[cH:54]1)[CH:55]1[CH2:56][CH2:57][CH2:58][N:59]([C:60]([O:61][CH:62]([CH3:63])[CH3:64])=[O:65])[c:66]2[cH:67][c:68]([NH2:69])[cH:70][cH:71][c:72]21)(=[O:73])[CH3:74]>>[C:1]([CH3:2])(=[O:3])[N:4]([CH:5]1[c:6]2[c:7]([c:18]([NH2:41])[cH:19][cH:20][cH:21]2)[N:8]([C:12](=[O:13])[O:14][CH:15]([CH3:16])[CH3:17])[CH2:9][CH2:10][CH2:11]1)[CH2:23][c:24]1[cH:25][c:26]([C:34]([F:35])([F:36])[F:37])[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e254e6c76d77475d8ec563ac20628775
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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