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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 112231Generated: October 27, 2026

1,2-Dimethoxyethane → 3-Chloro-5-(1,3-thiazol-2-ylethynyl)pyridine

https://huagongshe.com/reaction/112231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant2-BromothiazoleHCID 76430—
Reactant3-Chloro-5-ethynylpyridineHCID 23500887—
Product3-Chloro-5-(1,3-thiazol-2-ylethynyl)pyridineHCID 23500886—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-60adf46f770b41748fd3b251ee86b2b8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)