Methanol → 6-[(3-Sulfamoyl-2,2-dimethylpropyl)thio]imidazo[1,2-b]pyridazine

HRID 1122354Notes

Reaction equation

HRID 1122354 reaction equation
[CH3:11][OH:12].[CH3:13][O-:14].[CH3:26][OH:27].[Cl:16][c:17]1[cH:18][cH:19][c:20]2[n:21]([n:22]1)[cH:23][cH:24][n:25]2.[Na+:15].[SH:1][CH2:2][C:3]([CH2:4][S:5](=[O:6])(=[O:7])[NH2:8])([CH3:9])[CH3:10]>>[S:1]([CH2:2][C:3]([CH2:4][S:5](=[O:6])(=[O:7])[NH2:8])([CH3:9])[CH3:10])[c:17]1[cH:18][cH:19][c:20]2[n:21]([n:22]1)[cH:23][cH:24][n:25]2

Participants

6

Reactant 5

HCID 887Methanol2×HCID 923Sodium ionHCID 138828Imidazo(1,2-b)pyridazine, 6-chloro-HCID 3826051MethoxideHCID 104649823-Mercapto-2,2-dimethyl-1-propylsulfonamide

Product 1

HCID 99720306-[(3-Sulfamoyl-2,2-dimethylpropyl)thio]imidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-194127801e73490c8e19ac7b41a180c3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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