5-Methyl-alpha-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamine → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [3-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-butyl]-amide

HRID 1122388Notes

Reaction equation

HRID 1122388 reaction equation
[CH3:21][c:22]1[n:23][c:24]([CH:27]([NH2:28])[CH2:29][CH:30]([CH3:31])[CH3:32])[n:25][o:26]1.[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:28][CH:27]([c:24]3[n:23][c:22]([CH3:21])[o:26][n:25]3)[CH2:29][CH:30]([CH3:31])[CH3:32])[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 435593295-Methyl-alpha-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamineHCID 710872926-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid

Product 1

HCID 711145386-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [3-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-butyl]-amide

Sources & evidence

ORD record
ord-a7dc7755978b40a49a288e9ed245bc34
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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