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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1122793Generated: October 31, 2026

Dimethylformamide → {2-[7-(2,4-Bis-trifluoromethyl-phenyl)-1H-indol-3-yl]-1,1-dimethyl-ethyl}-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1122793

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
Reactant2,4-Bis(trifluoromethyl)phenylboronic acidHCID 2782667—
Reactanttrifluoro-methanesulfonic acid 3-(2-tert-butoxycarbonylamino-2-methyl-propyl)-1H-indol-7-yl esterHCID 86595245—
Product{2-[7-(2,4-Bis-trifluoromethyl-phenyl)-1H-indol-3-yl]-1,1-dimethyl-ethyl}-carbamic acid tert-butyl esterHCID 86595246—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-50503a073f054e069b3d4ed431e32787
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)