5-Chloro-2-(3-cyanophenoxy)nicotinic acid → tert-butyl 4-[1-[[5-chloro-2-(3-cyanophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoate

HRID 1122798Notes

Reaction equation

HRID 1122798 reaction equation
[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][c:14]([C:18]#[N:19])[cH:15][cH:16][cH:17]2)[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[NH2:20][CH:21]([CH3:22])[c:23]1[cH:24][cH:25][c:26]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[cH:34][cH:35]1>>[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][c:14]([C:18]#[N:19])[cH:15][cH:16][cH:17]2)[c:6]([C:7](=[O:9])[NH:20][CH:21]([CH3:22])[c:23]2[cH:24][cH:25][c:26]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[cH:34][cH:35]2)[cH:10]1

Participants

3

Reactant 2

HCID 575722665-Chloro-2-(3-cyanophenoxy)nicotinic acidHCID 59478590Tert-butyl 4-(1-aminoethyl)benzoate

Product 1

HCID 178464838tert-butyl 4-[1-[[5-chloro-2-(3-cyanophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoate

Sources & evidence

ORD record
ord-861b6b88cd6f444fbaccb1c078388a62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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