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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 112280Generated: October 29, 2026

Hydrochloric Acid → 7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-[1-(1-methyl-1H-pyrazol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carboxamide

https://huagongshe.com/reaction/112280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPhosgeneHCID 6371—
Reactantalpha,1-Dimethyl-1H-pyrazole-3-methanamineHCID 19616543—
Reactant4-(4-Methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amineHCID 49779438—
Product7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-[1-(1-methyl-1H-pyrazol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carboxamideHCID 59496606—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-55a9612dca3d4a51a9a414bc22c72b70
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)