Acetone → 7-[3-(4-acetylpiperazin-1-yl)propoxy]-4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinazoline
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][CH2:12][O:13][c:14]2[c:15]([O:25][CH3:26])[cH:16][c:17]3[c:18]([Cl:24])[n:19][cH:20][n:21][c:22]3[cH:23]2)[CH2:8][CH2:9]1.[C:39](=[O:40])([O-:41])[O-:42].[CH3:45][C:46](=[O:47])[CH3:48].[Cs+:43].[Cs+:44].[F:27][c:28]1[c:29]2[cH:30][c:31]([CH3:38])[nH:32][c:33]2[cH:34][cH:35][c:36]1[OH:37]>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][CH2:12][O:13][c:14]2[c:15]([O:25][CH3:26])[cH:16][c:17]3[c:18]([O:37][c:36]4[c:28]([F:27])[c:29]5[cH:30][c:31]([CH3:38])[nH:32][c:33]5[cH:34][cH:35]4)[n:19][cH:20][n:21][c:22]3[cH:23]2)[CH2:8][CH2:9]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a7f7d64f526f4946b25608bb4ca255ff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…