Ethanol → 6-[[[4-fluoro-1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]pyrrolidin-3-yl]methylamino]methyl]-4H-pyrido[3,2-b][1,4]thiazin-3-one
Reaction equation
[CH3:40][CH2:41][OH:42].[Cl:37][CH2:38][Cl:39].[F:1][CH:2]1[CH:3]([CH2:22][NH2:23])[CH2:4][N:5]([CH2:7][CH2:8][c:9]2[c:10]([F:21])[cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([O:19][CH3:20])[n:17][c:18]23)[CH2:6]1.[O:24]=[C:25]1[CH2:26][S:27][c:28]2[c:29]([n:31][c:32]([CH:35]=[O:36])[cH:33][cH:34]2)[NH:30]1>>[F:1][CH:2]1[CH:3]([CH2:22][NH:23][CH2:35][c:32]2[n:31][c:29]3[c:28]([cH:34][cH:33]2)[S:27][CH2:26][C:25](=[O:24])[NH:30]3)[CH2:4][N:5]([CH2:7][CH2:8][c:9]2[c:10]([F:21])[cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([O:19][CH3:20])[n:17][c:18]23)[CH2:6]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-51d0b6ec7af7450980d117fb1be4f525
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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